In this experimental film, British actor Boris Karloff (1887-1969) embodies over 170 characters, experiencing a schizophrenic horror trip in which he faces versions of himself in different masks, at different ages, of different genders and races. As Karloff’s career spans over 50 years, from the silent era to modern-day cinema, A Masque of Madness allows us to witness the aesthetic and technical developments of the medium in one single film.