When he was 12 years old, Bill Cody, later knew as Buffalo Bill, is rider for "pony express" carrying the mail through the wilds of America. It becomes later caravans guide. When driving one of them meets Luisa, the niece of a priest who tried to evangelize the savage tribes accompanied by a converted Indian. It is a dangerous time because, before the advancing white man, the Sioux tribes are buying weapons from unscrupulous dealers...
Buffalo Bill Cody
Wild Bill Hickok
Calamity Jane
Pastor Norman Lieberman
Ethel Lieberman
Ted
Luisa
Guillermo
Colonel Carr
Dittle
St. James
Agnes St. James
Frank North
Steve
Red Cloud
Douglas
Utter
Charlie
Señorita Mortimer
Chica de saloon
Russell
Majors
Waddell
Mortimer
Padre de Bill
Madre de Bill
Hija de Steve